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2006 Mercedes-Benz S65 AMG V12 for sale

If you don’t have more cylinders than your neighbor are you even trying? It’s probably time to spring for a V12. This 2006 Mercedes-Benz S65 AMG is an absolute beast! How do you feel about 604 horsepower and 738 lb-ft of torque?

Model: 2006 Mercedes-Benz S65 AMG
Location: Leesburg, Virgnia
Miles: 85,375
Price: $19,987
Seller Type: Dealer, Leesburg Auto Import
Listed On: Facebook Marketplace and Leesburg Auto Import
Something Unique: 2006 W220 with a V12, stateside!

2006 Mercedes-Benz S65 AMG Rundown

The power plant at the peak of Mercedes-Benz S-class trims is a twin-turbocharged 6.0-liter V 12. It’ll still do a claimed 0-60 in 4.2 seconds. The real-world numbers are probably closer to 4.5 seconds but that’s still moving!

It is an S-Class, so it has got to be buttoned down, refined, and have a hefty curb weight as a result. Although there were some complaints within the community about the final quality and seat comfort. Nothing answers those questions like a test drive.

As is customary for AMGs, no third pedal here. We’ve got the not spry 5-speed automatic transmission. The 772.6 transmission is beefy, and capable of handling more power if you want a little extra bump.

You’re not going to be tossing this thing around any hairpins. You will be getting down I-85 much, much quicker.

S65 front view with older style headlamps

With the electronic limit of 155 mph removed, on a private course, you’re looking at the chance to hit over 180 mph. You may even clip 200 mph if you’re brave and have a tune. For a car with rear seats and legitimate rear leg room, that’s a tad excessive.

black rear seats in S65

This level of performance, the ability to move your family around, and having 12 cylinders to brag about for around 20k? There’s a reason the 2006 model year S65 AMG is a rare and tough find. Stateside, the W220 S65 AMG was only sold for just that year, 2006.

S65 Condition

With 85,000 miles, this well could be one of the lowest mileage examples left around. Mechanically, it seems to be well sorted. Cosmetically, it’s not perfect but it is not an eyesore.

Rear quarter panel view with amg wheels and S65 badge

I’d love for this care to be black but you can’t win them all. You can always wrap it? Maybe that’s sacrilege, I don’t know. The AMG wheels look to be in pretty good shape with some curb rash present. I’m a huge fan of the double spokes.

2006 Mercedes-Benz S65 grey right
small bit of curb rash if you zoom in

The interior is in decent condition. It obviously shows signs of wear, but at least the wood trim isn’t falling off.

The W220’s were notorious for some of their more advanced electronics failing. Your mileage and level of importance may vary, but I wouldn’t expect all the gadgets to just work. The listing doesn’t point out any specifics but keep that in mind when going to check it out.

2006 Mercedes-Benz S65 cockpit

The leather has held up reasonably well in the front leg room heavy seats. The driver’s side bolster does show the most wear, which is typical.

Front seats showing a little bit of wear on the driver's side
some wear on the far side of the driver seat

The standard equipment on this 06 S65 includes heated and ventilated front seats, Bi-Xenon headlights, Active Body Control, and AMG side skirts that bleed the early 2000s.

Even by today’s standards, it’s a well-equipped car. I’ve never had ventilated seats… With leather seats in the summer, I’m sure that’d be a nice change. Swamps are not very fun places. Hope they work!

Recent Service

It is sitting on a new set of Michelin Pilot Sport 4S, a very solid street tire. Though in the winter you’re going to need to be pretty careful on those. Don’t be that person fishtailing out of Cars and Coffee into a telephone pole. I mean, we all like watching videos of that, but yeah – don’t do it.

AMG dual-spoke wheels with pilot sport 4s

The Dealer and CarFax show it’s recently had:

  • Powertrain Control Module replaced
  • Rear brake pads replaced
  • Oil and filter changed
  • Spark plugs replaced

In Mercedes land, that’s at least a couple of grand in work. Gotta pay to play, drive, and use the car. It’s a 17 year old V12, what do you want? It’s doing the best it can. We all tell our kids that’s enough, right?

There’s no way you’re touching these specs in new cars without paying over $100k. I’d seriously consider picking this up, getting a PPI first, and using that other $80k for maybe a fun BMW M car, Porsche Cayman or 911, OR contributions to Top Car Finds…


In all seriousness, normally these are only popping up on Cars and Bids or Bring a Trailer. It’s pretty rare to see one offered at a dealership.

There is an accident and body damage report in the CarFax, but it still has a clean title. Again, post PPI, maybe use that accident history to your advantage?

2006 Mercedes-Benz S65 quad exhaust

The folks at Leesburg do have it at a pretty solid price in my humble opinion. I’m not affiliated in any way, and make no kickbacks, for saying that. (Nobody but us even knows this site exists yet!)

I think there’s a solid deal in here though if you’re comfortable with a little bit of risk. At least sneak a test drive in, and see if you’re not convinced.

In the automatic transmission world, what else are you gonna do anyway with $20k? I guess probably another AMG, maybe a wagon?